Oct 01, 2020
The SFB researchers Valérie Hilgers (project B04), Dominika Grzejda (project B04), Carlos-Alfonso Gonzalez (project B04) and others could show that the two neuron-specific RNA-binding proteins ELAV and FNE define the unique identity of neuronal messenger RNAs. When not repressed by ELAV, FNE undergoes a functional switch and rescues neuronal RNA processing in a process termed exon- activated functional rescue. Publication in Molecular Cell.
