The SFB 1381 investigates how different proteins are dynamically assembled into complex multimers, the so-called protein machineries, which play a central role e.g. in the energy metabolism of the cell, the replication, repair, and transcription of DNA, the folding and degradation of proteins, as well as the intra- and intercellular communication and transport processes. The focus of the SFB 1381 lies on the organization of these protein machineries in modular units, the regulation of their assembly and disassembly, and the impact of these processes on cellular functions.
The aim of the SFB 1381 is to define and understand the dynamic processes of the assembly and organization of cellular protein machineries, and to gain insight into the fundamental processes in a living cell.
In this workshop, organized by SFB 1381 and GRK 2606, SFB 1381 PI Prof. Dr. Oliver Einsle will introduce the fundamentals in structural biology and give an introduction to AlphaFold.
On June 2nd and 3rd, 2022, 23 PhD students and Postdocs took part in this year’s Young Researchers’ Retreat. Mohd Areeb describes the retreat as a great opportunity “to enjoy science and to get to know each other after a long pandemic break”. We can only agree!
In an interview, Asifa Akhtar, SFB 1381 PI and Vice Speaker, talks about diversity in the Max Planck Society. SFB 1381 undertakes various measures to promote equal opportunities for all, thereby creating a welcoming atmosphere for all researchers joining our SFB.
SFB 1381 PI Sonja-Verena Albers (Project A01) was elected as a new member of the German National Academy of Sciences – Leopoldina in May 2022.
SFB 1381 is happy to announce and host the event “Women in Science” which takes place on 29.6.2022 at 4:15 pm.
In June 2022, SFB 1381 PhD students and Postdocs are finally able to have an in-person retreat. The retreat will be taking place in Gutach-Bleibach, a small village in the Black Forest.
As a partner of Pint of Science Freiburg, we are happy to announce this year’s program. On May 9th, 10th and 11th, 2022, nine talks (in German and English) covering various topics are scheduled at Borso Bar in Freiburg.
SFB 1381 offers this online-workshop for PhD students and Postdocs who are interested in working on their skills needed for Poster Presentations. This workshop takes place in May 2022.
Congratulations to Hans-Georg Koch (Project B06), Sonja Albers (Project A01) and Matthias Boll (Project A03): their article “The missing enzymatic link in syntrophic methane formation from fatty acids” was recognized as a finalist for the 2021 Cozzarelli Prize!
Our first SFB 1381 symposium “Dynamic Organization of Cellular Protein Machineries” was held from March 9-11, 2022 in an online format.
Vögtle, F.N., Koch, H.G., and Meisinger, C. (2022) A common evolutionary origin reveals fundamental principles of protein insertases. PLoS Biol 20(3), e3001558
Morgenstern, M., Peikert, C.D., Lübbert, P., Suppanz, I., Klemm, C., Alka, O., Steiert, C., Naumenko, N., Schendzielorz, A., Melchionda, L., Mühlhäuser, W.W.D., Knapp, B., Busch, J.D., Stiller, S.B., Dannenmaier, S., Lindau, C., Licheva, M., Eickhorst, C., Galbusera, R., Zerbes, R.M., Ryan, M.T., Kraft, C., Kozjak-Pavlovic, V., Drepper, F., Dennerlein, S., Oeljeklaus, S., Pfanner, N., Wiedemann, N., and Warscheid, B. (2021) Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context. Cell. Metab. 33(12), 2464-2483, e18
Yousefi, O.S., Ruggieri, M., Idstein, V., von Prillwitz, K.U., Herr, L.A., Chalupsky, J., Köhn, M., Weber, W., Timmer, J., and Schamel, W.W.A. (2021) Cross-TCR Antagonism Revealed by Optogenetically Tuning the Half-Life of the TCR Ligand Binding. Int. J. Mol. Sci. 22, 4920
Agne, M., Estelmann, S., Seelmann, C. S., Kung, J., Wilkens, D., Koch, H.G., van der Does, C., Albers, S. V., von Ballmoos, C., Simon, J., and Boll, M. (2021) The missing enzymatic link in syntrophic methane formation from fatty acid. Proc. Natl. Acad. Sci. U S A 118(40), e2111682118