Projects

Research Area A: Formation and Organization of Membrane-Bound Protein Machineries

Prof. Dr. Sonja-Verena Albers

Dynamic Assembly and Rotation of the Archaellum Motor Complex

Prof. Dr. Annegret Wilde

Light-Dependent Dynamics in the Assembly of the Cyanobacterial Motility Machinery

Prof. Dr. Matthias Boll

Assembly and Dynamic Interactions of a 1 MDa Membrane Metalloenzyme Machinery Catalyzing a Key Step in Global Aromatic Ring Degradation

Prof. Dr. Oliver Einsle

Maturase Assemblies in Cytochrome c Biogenesis

Prof. Dr. Carola Hunte

Assembly and Biogenesis of Respiratory Complex III and of Related Supercomplexes

Prof. Dr. Maja Köhn
Prof. Dr. Chris Meisinger

Regulation of Biogenesis and Function of the Mitochondrial Protein Import Machinery by Phosphorylation

Prof. Dr. Nils Wiedemann

Modular Organisation of the Machinery for Membrane Insertion of Mitochondrial Beta-Barrel Proteins

Prof. Dr. Bernd Fakler

Biogenesis and Activity-Dependent Dynamics of AMPA-Receptor Complexes

Prof. Dr. Wolfgang Schamel

Biogenesis and Dynamic Regulation of TCR Assemblies

Research Area B: Dissection of Regulatory Networks

Prof. Dr. Roland Schüle

The KMT9 Protein Machinery is a Novel Chromatin Writer

Dr. Valérie Hilgers

Assembly, Dynamics and Function of ELAV Protein Machineries in Neurons

Dr. Asifa Akhtar

Identification and Characterization of MOF Interaction and Substrate Repertoire in Mammalian Cells

Prof. Dr. Nora Vögtle

Functional and Regulatory Network of the Mitochondrial Presequence Processing Machinery

Prof. Dr. Bettina Warscheid

Crosstalk between the Mitochondrial Respiratory Chain and the Cytosolic Protein Synthesis Machinery

Prof. Dr. Hans-Georg Koch

Adaptive Remodeling of Ribosome Composition and Function in Response to Metabolic Changes and Cellular Stress

Prof. Dr. Thorsten Hugel

Structures and Dynamics of the Hsp90 Machinery

Prof. Dr. Sabine Rospert

Partitioning of the Hsp70 Ssb between Ribosomes and Cytosolic Chaperone Machineries

Prof. Dr. Ralf Baumeister

mTOR and Ribonucleoprotein Complex Dynamics under Stress

Prof. Dr. Claudine Kraft

Dynamic Assembly of the Atg1 Kinase Complex during Autophagosome Biogenesis

Associated Projects

Dr. Laura Gámez-Díaz

Dynamics of LRBA Machinery in Autophagy and Vesicle Trafficking

Dr. Sascha Yousefi

Analysis of Dynamic Signalosome Assembly upon Optogenetically Controlled T cell Signal Input

Prof. Dr. Jens Timmer

Mathematical Modelling of Cellular Protein Machineries

Jun. Prof. Dr. David Haselbach

Cryo-Electron Microscopy of Dynamic Protein Machineries

Prof. Dr. Thomas Ott

Correlative Imaging of Protein Complexes

Dr. Friedel Drepper

Mass Spectrometry Platform for Analysis of Dynamic Protein Machineries

Dr. Khaled Selim

Assembly/Disassembly Dynamics and Molecular organization of PII-Signaling Machinery

Central Projects

Dr. Uwe Schulte
Prof. Dr. Bettina Warscheid

High-Resolution Proteomics of Dynamic Protein Machineries

Get in contact

Coordinator
Dr. Verena Puxbaum
Institute of Biochemistry and Molecular Biology
University of Freiburg

+49 (0) 761 / 203-97441 sfb1381@biochemie.uni-freiburg.de

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