Light-Dependent Dynamics in the Assembly of the Cyanobacterial Motility Machinery

Project Summary

Bacterial movement using type IV pili relies on dynamic, polar assembly of the motility machinery in order to move into a certain direction. In cyanobacterial phototaxis, localized control of pilus activity by light gives us a unique opportunity to probe the assembly dynamics of this molecular machine. In this project, we want to determine the molecular components of the cyanobacterial motility machinery and understand the dynamics of pilus motor biogenesis and its communication with the phototaxis signaling complexes.