Imaging Dynamics of Protein Machineries and Correlation with Cellular Topologies

Project Summary

Cell imaging provides spatial and temporal resolution and can resolve dynamic changes within protein assemblies in real time and in living cells. We will provide different state-of-the-art imaging techniques (fluorescence microscopy, Airy-Scan-microscopy, TIRFM, electron microscopy) and advanced FLIM-FRET and TEM approaches to enable visualization of topological changes in the direct cellular environment. We will also support the SFB PIs during data acquisition and with quantitative image analysis.