A recent workshop titled “Practical Approaches to Protein Structure Prediction: AlphaFold and More“, led by Dr. Florian Schneider from project A04, brought together early career researchers to explore emerging tools and techniques in computational protein structure prediction – an area central to our SFB. Participants received an overview of structural biology and gained insights into how modern prediction methods are reshaping biochemical research.
A key feature of the event was a hands-on session with Boltz2. Attendees practiced running predictions, interpreting structural models, and identifying common challenges. Many participants worked with their own datasets, receiving direct guidance on applying their tool of choice to their scientific questions.
The program also introduced complementary approaches, including local installations, community servers, and additional tools such as Alphafold2/3, Chai-1 and AlphaPulldown. These sessions offered a broader view of the current computational landscape and how different methods can support experimental research.
The workshop concluded with a discussion on future developments, highlighting the growing role of predictive modeling in understanding complex protein machineries.
A big thank you to Florian for organizing and hosting the workshop!
