Research

Publications

Pessoa Rodrigues, C., Herman, J.S., Herquel, B., Valsecchi, C.I.K., Stehle, T., Grün, D., and Akhtar, A. (2020) Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Sci. Adv. 6, eaaz4815

Pathan-Chhatbar, S., Drechsler, C., Richter, K., Morath, A., Wu, W., OuYang, B., Xu, C., and Schamel, W.W. (2020) Direct Regulation of the T Cell Antigen Receptor’s Activity by Cholesterol. Front. Cell Dev. Biol. 8, 615996

Ye, X., Vogt, M.S., van der Does, C., Bildl, W., Schulte, U., Essen, L.O., and Albers, S.V. (2020) The Phosphatase PP2A Interacts With ArnA and ArnB to Regulate the Oligomeric State and the Stability of the ArnA/B Complex. Front. Microbiol. 11, 1849

Schwenk, J., and Fakler, B. (2020) Building of AMPA-type glutamate receptors in the endoplasmic reticulum and its implication for excitatory neurotransmission. J. Physiol. 599(10), 2639-2653

Schummer, A., Maier, R., Maskit, S., Hansen, T., Mühlhäuser, W.D., Suppanz, I., Fadel, A., Schuldiner, M., Girzalsky, W., Oeljeklaus, S., Zalckvar, E., Erdmann, R., and Warscheid, B. (2020) Pex14p phosphorylation modulates import of citrate synthase 2 into peroxisomes in Saccharomyces cerevisiae. Front. Cell Dev. Biol. 8, 549451

Hollenstein, D.M., and Kraft, C. (2020) Autophagosomes are formed at a distinct cellular structure. Curr. Opin. Cell Biol. 65, 50-57

Schmid, S., and Hugel, T. (2020) Controlling protein function by fine-tuning conformational flexibility. eLife 9, e57180

Seelmann, C. S., Willistein, M., Heider, J., and Boll, M. (2020) Tungstoenzymes: Occurrence, catalytic diversity and cofactor synthesis. Inorganics 8, 44

Samata, M., Alexiadis, A., Richard, G., Georgiev, P., Nuebler, J., Kulkarni, T., Renschler, G., Basilicata, M.F., Zenk, F.L., Shvedunova, M., Semplicio, G., Mirny, L., Iovino, N., and Akhtar, A. (2020) Intergenerationally Maintained Histone H4 Lysine 16 Acetylation Is Instructive for Future Gene Activation. Cell 182(1), 127-144

Sheikh, B.N., Guhathakurta, S., Tsang, T.H., Schwabenland, M., Renschler, G., Herquel, B., Bhardwaj, V., Holz, H., Stehle, T., Bondareva, O., Aizarani, N., Mossad, O., Kretz, O., Reichardt, W., Chatterjee, A., Braun, L.J., Thevenon, J., Sartelet, H., Blank, T., Grün, D., von Elverfeldt, D., Huber, T.B., Vestweber, T., Avilov, S., Prinz, M., Buescher, J.M., and Akhtar, A. (2020) Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat. Cell Biol. 22(7), 828-841

Reimann, L., Schwäble, A.N., Fricke, A., Mühlhäuser, W.D., Leber, Y., Lohanadan, K., Puchinger, M., Schäuble, S., Fässler, E., Wiese, H., Reichenbach, C., Knapp, B., Peikert, C.D., Drepper, F., Hahn, U., Kreutz, C., van der Ven, P.F.M., Radziwill, G., Djinović-Carugo, K., Fürst, D.O., and Warscheid, B. (2020) Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C. Commun. Biol. 3, 253

Martín-Leal, A., Blanco, R., Casas, J., Sáez, M.E,, Rodríguez-Bovolenta, E., de Rojas, I., Drechsler, C., Real, L.M., Fabrias, G., Ruíz, A., Castro, M., Schamel, W.W., Alarcón, B., van Santen, H.M., and Mañes, S. (2020) CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesis. EMBO J. 39, e104749

Heimbucher, T., Qi, W., and Baumeister, R. (2020) TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS. Autophagy 16(6), 1154-1156

Gomkale, R., Cruz-Zaragoza, L.D., Suppanz, I., Guiard, B., Montoya, J., Pacheu-Grau, D., Warscheid, B., and Rehling, P. (2020) Defining the substrate spectrum of the TIM22 complex identifies pyruvate carrier subunits as unconventional cargos. Curr. Biol. 30(6), 1119-1127

Li, Z., Rodriguez-Franco, M., Albers, S.V., and Quax, T. (2020) The switch complex ArlCDE connects the chemotaxis system and the archaellum. Mol. Microbiol. 114, 468–479

Steinberg, R., Origi, A., Natriashvili, A., Sarmah, P., Licheva, M., Walker, P.M., Kraft, C., High, S., Luirink, J., Shi, W.Q., Helmstädter, M., Ulbrich, M.H., and Koch, H.G. (2020) Post-translational insertion of small membrane proteins by the bacterial signal recognition particle. PloS Biol. 18, e3000874