Research

Publications

Sheikh, B.N., Guhathakurta, S., Tsang, T.H., Schwabenland, M., Renschler, G., Herquel, B., Bhardwaj, V., Holz, H., Stehle, T., Bondareva, O., Aizarani, N., Mossad, O., Kretz, O., Reichardt, W., Chatterjee, A., Braun, L.J., Thevenon, J., Sartelet, H., Blank, T., Grün, D., von Elverfeldt, D., Huber, T.B., Vestweber, T., Avilov, S., Prinz, M., Buescher, J.M., and Akhtar, A. (2020) Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat. Cell Biol. 22(7), 828-841

Reimann, L., Schwäble, A.N., Fricke, A., Mühlhäuser, W.D., Leber, Y., Lohanadan, K., Puchinger, M., Schäuble, S., Fässler, E., Wiese, H., Reichenbach, C., Knapp, B., Peikert, C.D., Drepper, F., Hahn, U., Kreutz, C., van der Ven, P.F.M., Radziwill, G., Djinović-Carugo, K., Fürst, D.O., and Warscheid, B. (2020) Phosphoproteomics identifies dual-site phosphorylation in an extended basophilic motif regulating FILIP1-mediated degradation of filamin-C. Commun. Biol. 3, 253

Martín-Leal, A., Blanco, R., Casas, J., Sáez, M.E,, Rodríguez-Bovolenta, E., de Rojas, I., Drechsler, C., Real, L.M., Fabrias, G., Ruíz, A., Castro, M., Schamel, W.W., Alarcón, B., van Santen, H.M., and Mañes, S. (2020) CCR5 deficiency impairs CD4+ T-cell memory responses and antigenic sensitivity through increased ceramide synthesis. EMBO J. 39, e104749

Heimbucher, T., Qi, W., and Baumeister, R. (2020) TORC2-SGK-1 signaling integrates external signals to regulate autophagic turnover of mitochondria via mtROS. Autophagy 16(6), 1154-1156

Gomkale, R., Cruz-Zaragoza, L.D., Suppanz, I., Guiard, B., Montoya, J., Pacheu-Grau, D., Warscheid, B., and Rehling, P. (2020) Defining the substrate spectrum of the TIM22 complex identifies pyruvate carrier subunits as unconventional cargos. Curr. Biol. 30(6), 1119-1127

Li, Z., Rodriguez-Franco, M., Albers, S.V., and Quax, T. (2020) The switch complex ArlCDE connects the chemotaxis system and the archaellum. Mol. Microbiol. 114, 468–479

Steinberg, R., Origi, A., Natriashvili, A., Sarmah, P., Licheva, M., Walker, P.M., Kraft, C., High, S., Luirink, J., Shi, W.Q., Helmstädter, M., Ulbrich, M.H., and Koch, H.G. (2020) Post-translational insertion of small membrane proteins by the bacterial signal recognition particle. PloS Biol. 18, e3000874

Zhang, Y., Gesé, G.V., Conz, C., Lapouge, K., Kopp, J., Wölfle, T., Rospert, S., and Sinning, I. (2020) The ribosome-associated complex RAC serves in a relay that directs nascent chains to Ssb. Nat. Commun. 11(1), 1504

Makepeace, K.A.T., Mohammed, Y., Rudashevskaya, E.L., Petrotchenko, E.V., Vögtle, F.N., Meisinger, C., Sickmann, A., and Borchers, C.H. (2020) Improving Identification of In-organello Protein-Protein Interactions Using an Affinity-enrichable, Isotopically Coded, and Mass Spectrometry-cleavable Chemical Crosslinker. Mol. Cell. Proteomics 19, 624-639

Pacheu-Grau, D., Wasilewski, M., Oeljeklaus, S., Gibhardt, C.S., Aich, A., Chudenkova, M., Dennerlein, S., Deckers, M., Bogeski, I., Warscheid, B., Chacinska, A., and Rehling, P. (2020) COA6 facilitates cytochrome c oxidase biogenesis as thiol-reductase for copper metallochaperones in mitochondria. J. Mol. Biol. 432, 2067-2079

van Wolferen, M., Shajahan, A., Heinrich, K., Brenzinger, S., Black, I.M., Wagner, A., Briegel, A., Azadi, P., and Albers, S.V. (2020) Species-specific recognition of Sulfolobales mediated by UV-inducible pili and S-layer glycosylation patterns. mBio 11, e03014-19

Yousefi, O.S., Hörner, M., Wess, M., Idstein, V., Weber, W., and Schamel, W.W. (2020) Optogenetic Tuning of Ligand Binding to The Human T cell Receptor Using The opto-ligand-TCR System. Bio Protoc. 10(5), e3540

Haas, T.M., Qiu, D., Häner, M., Angebauer, L., Ripp, A., Singh, J., Koch, H.G., Jessen-Trefzer, C., and Jessen, H.J. (2020) Four Phosphates at One Blow: Access to Pentaphosphorylated Magic Spot Nucleotides and Their Analysis by Capillary Electrophoresis. J. Org. Chem. 85, 14496-14506

Ilik, I.A., Aktas, T., Maticzka, D., Backofen, R., and Akhtar, A. (2020) FLASH: ultra-fast protocol to identify RNA-protein interactions in cells. Nucleic Acids. Res. 48(3), e15

Baumert, H.M., Metzger, E., Fahrner, M., George, J., Thomas, R.K., Schilling, O., and Schüle, R. (2020) Depletion of histone methyltransferase KMT9 inhibits lung cancer cell proliferation by inducing non-apoptotic cell death. Cancer Cell Int. 20, 52

von Känel, C., Muñoz-Gómez, S.A., Oeljeklaus, S., Wenger, C., Warscheid, B., Wideman, J.G., Harsman, A., and Schneider, A. (2020) Homologue replacement in the import motor of the mitochondrial inner membrane of trypanosomes. eLife 9, e52560