Research

Publications

Velasco Cárdenas, R.MH., Brandl, S.M., Meléndez, A.V., Schlaak, A.E., Buschky, A.,  Peters, T., Beier, F., Serrels, B., Taromi, S., Raute, K., Hauri, S., Gstaiger, M., Lassmann, S., Huppa, J.B., Boerries, M., Andrieux, G., Bengsch, B., Schamel, W.W. and Minguet, S. (2023) Harnessing CD3 diversity to optimize CAR T cells. Nat. Immunol. 24, 2135–2149

Guhathakurta, S., Erdogdu, N. U., Hoffmann, J. J., Grzadzielewska, I., Schendzielorz, A., Seyfferth, J., Martensson, C. U., Corrado, M., Karoutas, A., Warscheid, B., Pfanner, N., Becker, T. and Akhtar, A. (2023) COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function. Nat Metab 5(11), 1931-1952

Portela, P. C., Morgado, L., Silva, M. A., Denkhaus, L., Einsle, O. and Salgueiro, C. A. (2023) Exploring oxidative stress pathways in Geobacter sulfurreducens: the redox network between MacA peroxidase and triheme periplasmic cytochromes. Front Microbiol 141253114

Idstein, V., Ehret, A. K., Yousefi, O. S. and Schamel, W. W. (2023) Engineering of an Optogenetic T Cell Receptor Compatible with Fluorescence-Based Readouts. ACS Synth Biol 12(10), 2857-2864

Rojas-Restrepo, J., Sindram, E., Zenke, S., Haberstroh, H., Mitsuiki, N., Gabrysch, A., Huebscher, K., Posadas-Cantera, S., Krausz, M., Kobbe, R., Rohr, J. C., Grimbacher, B. and Gamez-Diaz, L. (2023) Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry. J Clin Immunol 43(8), 2076-2089

Hollenstein, D. M., Maurer-Granofszky, M., Reiter, W., Anrather, D., Gossenreiter, T., Babic, R., Hartl, N., Kraft, C. and Hartl, M. (2023) Chemical Acetylation of Ligands and Two-Step Digestion Protocol for Reducing Codigestion in Affinity Purification-Mass Spectrometry. J Proteome Res 22(10), 3383-3391

Mondol, T., Silbermann, L.M., Schimpf, J., Vollmar, L., Hermann, B., Tych, K.K. and Hugel, T. (2023) Aha1 regulates Hsp90’s conformation and function in a stoichiometry-dependent way. Biophys J. 122(17), 3458-3468

Ilcu, L., Denkhaus, L., Brausemann, A., Zhang, L. and Einsle, O. (2023) Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat Commun 14(1), 5190

Tsang, T. H., Wiese, M., Helmstadter, M., Stehle, T., Seyfferth, J., Shvedunova, M., Holz, H., Walz, G. and Akhtar, A. (2023) Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Sci Adv 9(34), eadh5598

Lan, C., Kim, J., Ulferts, S., Aprile-Garcia, F., Weyrauch, S., Anandamurugan, A., Grosse, R., Sawarkar, R., Reinhardt, A. and Hugel, T. (2023) Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation. Nat. Commun. 14(1), 4831

Odermatt, P. D., Nussbaum, P., Monnappa, S., Tala, L., Li, Z., Sivabalasarma, S., Albers, S. V. and Persat, A. (2023) Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow. Curr Biol 33(15), 3265-3271 e3264

Fielden, L.F., Busch, J.D., Merkt, S.G., Ganesan, I., Steiert, C., Hasselblatt, H.B., Busto, J.V., Wirth, C., Zufall, N., Jungbluth, S., Noll, K., Dung, J.M., Butenko, L., von der Malsburg, K., Koch, H.G., Hunte, C., van der Laan, M., and Wiedemann, N. (2023) Central role of Tim17 in mitochondrial presequence protein translocation. Nature 621, 627–634

Denkhaus, L., Siffert, F. and Einsle, O. (2023) An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens. FEMS Microbiol Lett 370

Xu, F., Li, R., von Gromoff, E. D., Drepper, F., Knapp, B., Warscheid, B., Baumeister, R. and Qi, W. (2023) Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans. Nat Commun 14(1), 4176

Becker, F., Fuchs, S., Refisch, L., Drepper, F., Bildl, W., Schulte, U., Liang, S., Heinicke, J. I., Hansen, S. C., Kreutz, C., Warscheid, B., Fakler, B., Mymrikov, E. V. and Hunte, C. (2023) Conformational regulation and target-myristoyl switch of calcineurin B homologous protein 3. Elife 12

Iyer, S. S., Sun, Y., Seyfferth, J., Manjunath, V., Samata, M., Alexiadis, A., Kulkarni, T., Gutierrez, N., Georgiev, P., Shvedunova, M. and Akhtar, A. (2023) The NSL complex is required for piRNA production from telomeric clusters. Life Sci Alliance 6(9),