Research

Publications

Minguet, S., Maus, M.V. and Schamel, W.W. (2025) From TCR fundamental research to innovative chimeric antigen receptor design. Nat. Rev. Immunol. 25, 212-224

Grzejda, D., Hess, A., Rezansoff, A., Gorey, S., Carrasco, J., Alfonso-Gonzalez, C., Tsagkris, S., Neuhaus, L., Shi, M., Ozbulut, H.C., Vögtle, F.N., Vlachos, A. and Hilgers, V. (2025) Pumilio differentially binds to mRNA 3′ UTR isoforms to regulate localization of synaptic proteins. EMBO Rep. 1-24-24

Saller, B. S., Wohrle, S., Fischer, L., Dufossez, C., Ingerl, I. L., Kessler, S., Mateo-Tortola, M., Gorka, O., Lange, F., Cheng, Y., Neuwirt, E., Marada, A., Koentges, C., Urban, C., Aktories, P., Reuther, P., Giese, S., Kirschnek, S., Mayer, C., Pilic, J., Falquez-Medina, H., Oelgeklaus, A., Deepagan, V. G., Shojaee, F., Zimmermann, J. A., Weber, D., Tai, Y. H., Crois, A., Ciminski, K., Peyronnet, R., Brandenburg, K. S., Wu, G., Baumeister, R., Heimbucher, T., Rizzi, M., Riedel, D., Helmstadter, M., Buescher, J., Neumann, K., Misgeld, T., Kerschensteiner, M., Walentek, P., Kreutz, C., Maurer, U., Rambold, A. S., Vince, J. E., Edlich, F., Malli, R., Hacker, G., Kierdorf, K., Meisinger, C., Kottgen, A., Jakobs, S., Weber, A. N. R., Schwemmle, M., Gross, C. J. and Gross, O. (2025) Acute suppression of mitochondrial ATP production prevents apoptosis and provides an essential signal for NLRP3 inflammasome activation. Immunity 58, 90-107 e111

Franke, P., Freiberger, S., Zhang, L. and Einsle, O. (2025) Conformational protection of molybdenum nitrogenase by Shethna protein II. Nature 637, 998-1004

Licheva, M., Pflaum, J., Babic, R., Mancilla, H., Elsässer, J., Boyle, E., Hollenstein, D.M., Jimenez-Niebla, J., Pleyer, J., Heinrich, M., Wieland, F.G., Brenneisen, J., Eickhorst, C., Brenner, J., Jiang, S., Hartl, M., Welsch, S., Hunte, C., Timmer, J., Wilfling, F. and Kraft, C. (2025) Phase separation of initiation hubs on cargo is a trigger switch for selective autophagy. Nat. Cell Biol. 27, 283-297

Njenga, R.K., Boele, J., Drepper, F., Sinha, K., Marouda, E., Huesgen, P.F., Blaby-Haas, C. and Koch, H.G. (2024) Ribosome-inactivation by a class of widely distributed C-tail anchored membrane proteins. Structure 32, 2259-2275 e6

Ganesan, I., Busto, J.V., Pfanner, N. and Wiedemann, N. (2024) Biogenesis of mitochondrial beta-barrel membrane proteins. FEBS Open Bio. 14, 1595-1609

Marada, A., Walter, C., Suhm, T., Shankar, S., Nandy, A., Brummer, T., Dhaouadi, I., Vögtle, F.N. and Meisinger, C. (2024) DYRK1A signalling synchronizes the mitochondrial import pathways for metabolic rewiring. Nat. Commun. 15, 5265

Zhang, L. and Einsle, O. (2024) Architecture of the RNF1 complex that drives biological nitrogen fixation. Nat. Chem. Biol. 20, 1078-1085

Gaines, M.C., Sivabalasarma, S., Isupov, M.N., Haque, R.U., McLaren, M., Hanus, C., Gold, V.A.M., Albers, S.V. and Daum, B. (2024) CryoEM reveals the structure of an archaeal pilus involved in twitching motility. Nat. Commun. 15, 5050

Jiang, H., Milanov, M., Jungert, G., Angebauer, L., Flender, C., Smudde, E., Gather, F., Vogel, T., Jessen, H. J. and Koch, H.G. (2024) Control of a chemical chaperone by a universally conserved ATPase. iScience 27, 110215

Eickhorst, C., Babic, R., Rush-Kittle, J., Lucya, L., Lami Imam, F., Sanchez-Martin, P., Hollenstein, D.M., Michaelis, J., Munch, C., Meisinger, C., Slade, D., Gamez-Diaz, L. and Kraft, C. (2024) FIP200 phosphorylation regulates late steps in mitophagy. J. Mol. Biol. 436, 168631

Woessner, N.M., Brandl, S.M., Hartmann, S., Schamel, W.W., Hartl, F.A. and Minguet, S. (2024) Phospho-mimetic CD3epsilon variants prevent TCR and CAR signaling. Front. Immunol. 15, 1392933

Zhan, T., Jacoby, C., Jede, M., Knapp, B., Ferlaino, S., Gunter, A., Drepper, F., Muller, M., Weber, S. and Boll, M. (2024) Bacterial stigmasterol degradation involving radical flavin delta-24 desaturase and molybdenum-dependent C26 hydroxylase. J. Biol. Chem. 300, 107243

Kabelitz, D., Cierna, L., Juraske, C., Zarobkiewicz, M., Schamel, W.W. and Peters, C. (2024) Empowering gammadelta T-cell functionality with vitamin C. Eur. J. Immunol. 54, e2451028

Busto, J. V., Ganesan, I., Mathar, H., Steiert, C., Schneider, E.F., Straub, S. P., Ellenrieder, L., Song, J., Stiller, S.B., Lubbert, P., Chatterjee, R., Elsaesser, J., Melchionda, L., Schug, C., den Brave, F., Schulte, U., Klecker, T., Kraft, C., Fakler, B., Becker, T. and Wiedemann, N. (2024) Role of the small protein Mco6 in the mitochondrial sorting and assembly machinery. Cell Rep. 43, 113805