Research

Publications

Einsle, O. (2023) Catalysis and structure of nitrogenases. Curr. Opin. Struct. Biol. 83, 102719

Sun, Y., Wiese, M., Hmadi, R., Karayol, R., Seyfferth, J., Martinez Greene, J. A., Erdogdu, N. U., Deboutte, W., Arrigoni, L., Holz, H., Renschler, G., Hirsch, N., Foertsch, A., Basilicata, M. F., Stehle, T., Shvedunova, M., Bella, C., Pessoa Rodrigues, C., Schwalb, B., Cramer, P., Manke, T. and Akhtar, A. (2023) MSL2 ensures biallelic gene expression in mammals. Nature 624, 173-181

Velasco Cárdenas, R.MH., Brandl, S.M., Meléndez, A.V., Schlaak, A.E., Buschky, A.,  Peters, T., Beier, F., Serrels, B., Taromi, S., Raute, K., Hauri, S., Gstaiger, M., Lassmann, S., Huppa, J.B., Boerries, M., Andrieux, G., Bengsch, B., Schamel, W.W. and Minguet, S. (2023) Harnessing CD3 diversity to optimize CAR T cells. Nat. Immunol. 24, 2135-2149

Guhathakurta, S., Erdogdu, N. U., Hoffmann, J. J., Grzadzielewska, I., Schendzielorz, A., Seyfferth, J., Martensson, C. U., Corrado, M., Karoutas, A., Warscheid, B., Pfanner, N., Becker, T. and Akhtar, A. (2023) COX17 acetylation via MOF-KANSL complex promotes mitochondrial integrity and function. Nat. Metab. 5, 1931-1952

Portela, P. C., Morgado, L., Silva, M. A., Denkhaus, L., Einsle, O. and Salgueiro, C. A. (2023) Exploring oxidative stress pathways in Geobacter sulfurreducens: the redox network between MacA peroxidase and triheme periplasmic cytochromes. Front. Microbiol. 14, 1253114

Idstein, V., Ehret, A. K., Yousefi, O. S. and Schamel, W. W. (2023) Engineering of an Optogenetic T Cell Receptor Compatible with Fluorescence-Based Readouts. ACS Synth. Biol. 12, 2857-2864

Rojas-Restrepo, J., Sindram, E., Zenke, S., Haberstroh, H., Mitsuiki, N., Gabrysch, A., Huebscher, K., Posadas-Cantera, S., Krausz, M., Kobbe, R., Rohr, J. C., Grimbacher, B. and Gamez-Diaz, L. (2023) Functional Relevance of CTLA4 Variants: an Upgraded Approach to Assess CTLA4-Dependent Transendocytosis by Flow Cytometry. J. Clin. Immunol. 43, 2076-2089

Hollenstein, D. M., Maurer-Granofszky, M., Reiter, W., Anrather, D., Gossenreiter, T., Babic, R., Hartl, N., Kraft, C. and Hartl, M. (2023) Chemical Acetylation of Ligands and Two-Step Digestion Protocol for Reducing Codigestion in Affinity Purification-Mass Spectrometry. J. Proteome Res. 22, 3383-3391

Mondol, T., Silbermann, L.M., Schimpf, J., Vollmar, L., Hermann, B., Tych, K.K. and Hugel, T. (2023) Aha1 regulates Hsp90’s conformation and function in a stoichiometry-dependent way. Biophys. J. 122, 3458-3468

Ilcu, L., Denkhaus, L., Brausemann, A., Zhang, L. and Einsle, O. (2023) Architecture of the Heme-translocating CcmABCD/E complex required for Cytochrome c maturation. Nat. Commun. 14, 5190

Tsang, T. H., Wiese, M., Helmstadter, M., Stehle, T., Seyfferth, J., Shvedunova, M., Holz, H., Walz, G. and Akhtar, A. (2023) Transcriptional regulation by the NSL complex enables diversification of IFT functions in ciliated versus nonciliated cells. Sci. Adv. 9, eadh5598

Lan, C., Kim, J., Ulferts, S., Aprile-Garcia, F., Weyrauch, S., Anandamurugan, A., Grosse, R., Sawarkar, R., Reinhardt, A. and Hugel, T. (2023) Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation. Nat. Commun. 14, 4831

Odermatt, P. D., Nussbaum, P., Monnappa, S., Tala, L., Li, Z., Sivabalasarma, S., Albers, S. V. and Persat, A. (2023) Archaeal type IV pili stabilize Haloferax volcanii biofilms in flow. Curr. Biol. 33, 3265-3271 e3264

Fielden, L.F., Busch, J.D., Merkt, S.G., Ganesan, I., Steiert, C., Hasselblatt, H.B., Busto, J.V., Wirth, C., Zufall, N., Jungbluth, S., Noll, K., Dung, J.M., Butenko, L., von der Malsburg, K., Koch, H.G., Hunte, C., van der Laan, M., and Wiedemann, N. (2023) Central role of Tim17 in mitochondrial presequence protein translocation. Nature 621, 627-634

Denkhaus, L., Siffert, F. and Einsle, O. (2023) An unusual active site architecture in cytochrome c nitrite reductase NrfA-1 from Geobacter metallireducens. FEMS Microbiol. Lett. 370, nad068

Xu, F., Li, R., von Gromoff, E. D., Drepper, F., Knapp, B., Warscheid, B., Baumeister, R. and Qi, W. (2023) Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans. Nat. Commun. 14, 4176